Study report - GWAS of HIV-1 susceptibility (HGVST706)
|GWAS Central identifier||HGVST706|
|Study name||GWAS of HIV-1 susceptibility|
|Total markers imported||6|
|Study design||Case and control|
Illumina 1M-Duo chip|
|Abstract||To date, CCR5 variants remain the only human genetic factors to be confirmed to impact HIV-1 acquisition. However, protective CCR5 variants are largely absent in African populations, in which sporadic resistance to HIV-1 infection is still unexplained. We investigated whether common genetic variants associate with HIV-1 susceptibility in Africans.|
NHGRI GWAS catalog study annotation for HGVST706
|Key results||Not supplied|
|Reason for study size||Not supplied|
|Study power||Not supplied|
|Sources of bias||Not supplied|
Petrovski S, Fellay J, Shianna KV et al.
Common human genetic variants and HIV-1 susceptibility: a genome-wide survey in a homogeneous African population.
AIDS (London, England) 2011
Hindorff LA, Sethupathy P, Junkins HA et al.
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits.
Proceedings of the National Academy of Sciences U S A. 2009 May 27